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Product Info Summary
| SKU: | A02796 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-DPOG1 POLG Antibody
View all DNA Polymerase gamma Antibodies
SKU/Catalog Number
A02796
Size
100ul
Form
Liquid
Description
Boster Bio Anti-DPOG1 POLG Antibody catalog # A02796. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DPOG1 POLG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02796)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ROM-K around the phosphorylation site of S44.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02796 is reactive to POLG in Human, Mouse, Rat
Applications
A02796 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
139.562kDa
Background of DNA Polymerase gamma
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415.
Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767.
Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For POLG (Source: Uniprot.org, NCBI)
Gene Name
POLG
Full Name
DNA polymerase subunit gamma-1
Weight
139.562kDa
Superfamily
DNA polymerase type-A family
Alternative Names
DNA polymerase subunit gamma-1; EC 2.7.7.7; FLJ27114; MDP1; MIRAS; Mitochondrial DNA polymerase catalytic subunit; MTDPS4A; PolG, catalytic subunit; POLG1MTDPS4B; PolG-alpha; POLGAPEO; polymerase (DNA directed), gamma; SANDO; SCAE POLG MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO1, POLGA, SANDO, SCAE, POLG DNA polymerase gamma, catalytic subunit DNA polymerase subunit gamma-1|PolG-alpha|mitochondrial DNA polymerase catalytic subunit|mitochondrial polymerase gamma catalytic subunit|polymerase (DNA directed), gamma|polymerase (DNA) gamma, catalytic subunit|truncated mitochondrial DNA polymerase gamma catalytic subunit|truncated mitochondrial polymerase gamma catalytic subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on POLG, check out the POLG Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for POLG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DPOG1 POLG Antibody (A02796)
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No publications found for A02796
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Customer Reviews
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